Psoriasis is a chronic skin condition that affects millions of people worldwide. Common symptoms can include red, scaly patches of skin, itching, and burning. In severe cases, psoriasis can also lead to joint pain and swelling. While the condition is not life-threatening, patients with psoriasis may be more prone to developing certain health conditions due to the associated inflammation and insulin response. If left untreated, psoriasis can additionally lead to serious health complications, such as:

1. Psoriatic arthritis

Psoriatic arthritis is a form of arthritis that commonly develops in people with psoriasis. This is because people with psoriasis often have abnormal levels of certain immune system proteins in their blood. It is believed that these abnormal proteins trigger inflammation in the joints, which then leads to the symptoms of psoriatic arthritis. By targeting these proteins, Stelara is a medication that can reduce inflammation in the body, potentially preventing or treating psoriatic arthritis.

2. Chronic obstructive pulmonary disease (COPD)

COPD is a progressive lung disease that makes it difficult to breathe. Smoking is most often caused by smoking, but exposure to harmful particles or chemicals can increase the risk. In people with COPD, the airways become inflamed and begin to narrow. This can lead to mucus buildup, making breathing even more difficult. People with psoriasis have been found to be more likely to develop COPD than those without the disease. This is because the inflammation caused by psoriasis may damage the lungs and make them more vulnerable to COPD.

3. Lymphoma

One potential complication of psoriasis is lymphoma, a type of cancer that affects the lymphatic system. This occurs when abnormal cells grow in the lymph nodes and other tissues. While the exact cause is unknown, it is thought to develop when the body’s immune system becomes overactive. This can happen in response to an infection or to another trigger, such as psoriasis. Symptoms can include enlarged lymph nodes, fatigue, weight loss, and fever. If you have psoriasis, it is important to see a doctor for regular checkups to detect and treat any early signs of lymphoma. For example, your doctor may prescribe Otezla, which works by suppressing an overactive immune system.

4. Polycystic ovarian syndrome (PCOS)

Polycystic ovarian syndrome (PCOS) is a hormonal disorder that can cause various symptoms, including irregular periods, weight gain, and infertility. Though the exact cause of PCOS is unknown, it is thought to be related to an imbalance of insulin and testosterone hormones. It has also been shown that women with psoriasis are more likely to develop PCOS than women without skin conditions. One theory is that the inflammation caused by psoriasis may trigger an immune response that contributes to the development of PCOS. As such, women with psoriasis should be screened for PCOS if they experience any of the symptoms associated with the condition.

5. Depression

Depression is a serious mental illness that can negatively impact every facet of a person’s life. While the causes are complex and varied, research has shown a strong link between it and chronic medical conditions such as psoriasis. For many people, psoriasis is a minor annoyance. However, for some, the physical and emotional impact of the condition can be devastating. The constant itching, stinging, and burning can make everyday activities excruciating. In addition, the visible nature of the condition can lead to feelings of shame, isolation, and low self-esteem.

6. Heart disease

Though it most often manifests as a rash, psoriasis can also lead to the development of other health problems, including heart disease. Studies have shown that people with psoriasis are more likely to develop cardiovascular conditions such as heart attacks and strokes. One theory is that the inflammation associated with psoriasis may contribute to the buildup of plaque in the arteries.

Psoriasis is a serious condition that can profoundly impact a person’s health. While there is no cure, there are treatments available that can help to improve the symptoms and reduce inflammation. If you are living with psoriasis, talk to your doctor about the best treatment options available for you.